Serie Científica de Ann Erpino y Erik Winfree

Naturaleza / Sueños / Fauna / Ruinas / Espíritu Épocal

Retratos de la Ciencia y del Espíritu Interior de las Actividades Científicas

Las pinturas de esta serie dan una idea de la vida científica al combinar procesos, teorías, descubrimientos y conceptos científicos con algunos de los atributos e intereses personales de los científicos que los persiguen. La serie examina principalmente la notable complejidad, diversidad y capacidad de ingeniería de los procesos vivos, al mismo tiempo que presenta una variedad de conceptos científicos contemporáneos.

Cada imagen fue conceptualizada para un colega, mentor, estudiante, colaborador o asociado intelectual específico que enriqueció la vida científica del Dr. Erik Winfree. Cada imagen combina la ciencia que un individuo ha avanzado con algún aspecto de su carácter, sus intereses y pasatiempos, una teoría favorita, o alguna anécdota del tiempo que se pasó con Dr. Winfree.

Dr. Winfree instruyó a Ann en ciencia de vanguardia y le contó anécdotas de sus socios académicos y héroes, luego juntos conceptualizaron una pintura para cada uno. La serie original se exhibe ahora a Caltech.

INTELIGENCIA ARTIFICIAL


Las máquinas pueden ser programadas y ‘crecidas’ para hacer cosas útiles. Algún día podrían tener una especie de conciencia, una capacidad de atención si misma. Hoy ninguna máquina o tecnología se compara con la complejidad, la eficiencia, la capacidad de enfriamiento, o la elegancia de un cerebro real.

Aventuras en el Pensamiento Mecánico
Criatura Nervio
Cascada
BIOLOGIA Y BIOLOGÍA SINTÉTICA:

Los biólogos sintéticos pueden modificar y “diseñar” la información basada en la química codificada dentro del ADN de una célula para afectar el resultado de la función de la célula y sus interacciones con otras células. La tecnología moderna puede producir sistemas químicos sintéticos basados ​​en información con propiedades y capacidades comparables a las de los sistemas biológicos.

Bosque de Algas MarinasDescripciones de la Serie Winfree
Taller Molecular de Calderero
The nematode Caenorhabditis Elegans is mathematically unique in that wild-type individuals contain exactly 959 cells. The position of each cell is also precisely determined. C. Elegans is transparent, so cell function and lineage are easy to track.
959
Motor Citoesquelético
Pueblo de Vida
QUÍMICA

La química es el estudio de los elementos y compuestos, sus propiedades, composición, estructura y cómo se libera o absorbe la energía o qualque otra calidad cuando se cambian.

Puentes Cuánticos
Zoológico de Perlas
El Milagro del Hollín
Libélulas
Reacción – Difusión
At the human scale, a flat surface is a simple thing. But closer in, its incredible complexity becomes apparent. Molecular engineering can control some of that complexity, using self-assembly to coat the surface and place complex molecules in specific locations.
Campos Moleculares Para Siempre
When light bombards a molecule, a photon may be absorbed, in which case the extra energy causes the molecule's bonds to vibrate more vigorously. Some of that extra vibrational energy dissipates into the molecule's surroundings as heat. If the energy is not completely dissipated, the vibrations may align to create and emit a new photon with lower energy and a (usually) longer wavelength; that is, they fluoresce.
Fluorescencia
Molecules, molecular systems, and materials can be simulated and designed on computers, allowing visionary scientists to imagine and create environments from atoms on up.
De Que Están Hechos los Sueños
Gotita
COMPUTACIÓN

Nuestros cerebros análogas y los cerebros de muchos otros organismos tienen una mayor capacidad y eficiencia computacional que las computadoras. El reconocimiento de estampadas, abstracciones, algoritmos y la descomposición son cuatro facetas de nuestra conciencia computacional y procesos de pensamiento.

Computer chip technology is basically artificial geology. Lithography, the technique used to carve wires and transistors into a silicon chip, can build many layers of structures on a slab of silicon, but to truly master the art of turning inanimate rock into a thinking machine requires understanding the nature of the material. It will tell you what it can do; listen to the silicon.
Susurrador de Rocas
Cephalopond
Lluvia de Abstracciones
Discretización
Instantiación
The principle of least action states that, of all the possible paths a particle, such as a photon, could take, it will take the one with minimal integrated energy. Analogous optimization principles are used in software that finds the best route from place A to place B, finds the best price for a concert ticket, or finds the most likely interpretation of data.
El Mejor de Todos los Mundos Posibles
Indescifrable
EVOLUCIÓN Y EL ORIGEN DE LA VIDA

Vestigios y calidades fundamentales de nuestros primeros ancestros permanecen codificados dentro de nuestras células hoy. Ya sea planta o animal, hongo o virus, cada ser vivo culmina en una cadena muy larga, trayendo información desde tiempos primordiales. Todas las formas de vida conocidas comparten un solo ancestro común, un microbio que se cree que dio a luz los predecesores elementales de la maquinaria de la vida moderna, todavía presente en todas las células, como los ribosomas y el código genético. El ADN mitocondrial dentro de las células humanas es la firma genética que se transmite de madre a hijo. Hace unos 4 mil millones de años la Eva mitocondrial engendró una criatura cuya progenie finalmente se convirtió en humanoide y luego en humana.

Hagamos Esto
Unión / Escisión
La Pérdida de la Entropía
Inner Scaffolding - print only, 9x12
Andamios Interiores
Matriz Terrestre
We can't know how life started on Earth or how it starts elsewhere, but exploring how simple chemicals assemble, react, and evolve in the laboratory gives scientists an enriched and more grounded imagination for what the first organisms may have been like — and has already led to interesting biotechnologies.
Andy Ellington
Mymosh el Autoengendrado

SALUD Y MEDICINA

Los organismos son en diversos grados autocurativos. La ciencia y la tecnología pueden ayudar a los organismos a sanar, a veces mucho, y pueden diagnosticar, medir y monitorear aspectos de la enfermedad que los organismos normalmente no pueden observar.

Curadora Digital

Bailarina de Datos
Una Rasgadura en la Tela
Advanced medical therapies involve molecular robots programmed to 'crawl' around the outside of targeted cells (such as cancer cells) after recognizing diagnostic cell-surface markers that identify them as malign. As the molecule interacts with the cell membrane it effectively cuts it open, destroying the cell.
Proceso de Eliminación
MATEMÁTICAS

Las matemáticas son un ideal, una pureza, útil para estudiar e hipotetizar realidades físicas desordenadas. Las buenas matemáticas son cruciales para hacer observaciones y descubrimientos controlados. Se pueden definir objetos (como conjuntos o funciones) que son imposibles de calcular. En ausencia de acceso físico real a un problema, pueden ser adivinadas e incluso identificadas utilizando modelos matemáticos. Estos objetos imposibles pueden proporcionar información y claridad sobre lo que es posible o pragmático.

Fuerza de la Imposibilidad
Sombra de la Perfección
Casi Real
Mundo de Seifert
Retrato de Peter Gacs
Wings - print on canvas, 10x20
Alas
PROGRAMACIÓN MOLECULAR

Al usar estructuras de ARN en células vivas como sensores y controladores programables para el comportamiento celular, los científicos pueden diseñar y ‘crecer’ moléculas y estructuras moleculares que trabajan juntas para realizar funciones, como dentro de un circuito catalítico, montaje desencadenado, locomoción autónoma y más. Los programadores moleculares estudian los fundamentos y aplicaciones de la maquinaria molecular programable, desde modelos teóricos de computación basados ​​en bioquímica hasta el diseño experimental y la síntesis de dispositivos y sistemas complejos.

Conceptos Básicos
Jardines Colgantes
With the right insight and careful touch, DNA can Be programmed to assemble itself into incredibly complex nanoscale objects called 'DNA origami'.
La Tejedora
Bosque de Alambres
Cofre del Tesoro
People have long used biological materials -- skin, hair, bone, wood -- as the building material for crafting technological marvels -- leather boots, wool sweaters, ivory knives, sail boats. Today we're able to use biological polymers such as DNA, RNA, and protein to craft marvels at the molecular scale as well.
Fabricantes de JarronesDescripciones de la Serie Winfree
¡Capturados!
When informational molecules such as DNA, RNA, and proteins fold from a floppy linear chain into a concrete shape, such as an enzyme or other nanomachine, the process is directed by subsequences along the chain that search for matching subsequences elsewhere in the chain, and then bind and lock up to stabilize the fold.
Introspección MolecularDescripciones de la Serie Winfree
NEUROBIOLOGÍA

Organismos y individuos tienen muchas formas diversas de sentir, percibir y ser conscientes del mundo, dependiendo de su sensorio, ya sea ganglios, magnetorrecepticismo, ecolocalización, navegación o memoria celular. Los nervios humanos impregnan y afectan cada una de nuestras percepciones, funciones, respuestas, desarrollos y reflexiones. Las extensiones protoplásmicas extienden desde las puntas de las células nerviosas, las dendritas, y propagan la estimulación electroquímica recibida de otras células neurales, o las soma.

Bahía Theta
Sincronización
Homúnculo
Vista
SENDEROS PERSONALES
Nido de Roca
Consonancia y Disonancia

Cría

Occasionally someone’s life story may seem scripted or contrived to the point of being impossible - a series of extraordinary events, coincidences, great hardships and crucial choices leading to that person’s unique work and expertise, as if by recipe.
Contra Todo Pronóstico
Camino de la Mariposa





MISTERIOS Y FILOSOFIA DE LA CIENCIA









S. S. S.







Grün







Interdisciplinary science requires an ability to synthesize many strands of knowledge, to bind them together and test their strength, then extract pertinent information.
Fibra Arcoiris







Si Se Atreve







FÍSICA





Los físicos estudian las propiedades de la materia y la energía en el mundo natural: la dinámica del calor, la luz y otras radiaciones, la electricidad, el magnetismo y las micro y macropartículas.









Hoja de Arce







Capacidad Calorífica







Reinos Enredados 











Física en Formación







Compresión







Entremezclando







Tensegridad







ROBOTICA









Plan de 500 Años







Control theory studies how feedback loops between sensors and actuators can be used to make robust responsive systems, from a car’s cruise control to robots in a factory, or biochemical circuits within a cell.
Reaparición







Procesión Migratoria







Each of 100 trillion cells in your body has its own DNA, its own molecular factory for building proteins, and its own biochemical circuitry for making decisions. Though self-contained, these cells depend upon each other, and function together as a unified whole. Some species, such as slime molds, live as independent single-celled organisms in their early life, then unify with other slime mold cells into a multicellular organism for the latter part of their life. Roboticists may one day develop small robots that can similarly assemble themselves into a larger, unified meta-robot.
Juntamosnos







PROCESO CIENTIFICO





La ciencia es una disciplina, un esfuerzo, una aventura en lo extraño e inusual. Generaciones de científicos han refinado caminos de pensamiento duraderos a lo largo de los eones, desarrollando y construyendo sobre lo que sus predecesores descubrieron e inventaron. Generaciones de pensamiento científico e investigación han llevado a la comprensión actual del mundo que nos rodea.









Often the best scientific result is the simplest. A solution or discovery may, with hindsight, be so uncomplicated and obvious that it's surprising, or elegant. Yet to approach that simple truth may have required sophisticated instruments and complex methods to explore thousands of possibilities.
Una Mente Preparada







Notas Para Sí Mismo







Chemical processes can create patterns similar to the spots on leopards, the patchwork on giraffes, the stripes on zebras. More complex patterns could be created if chemistry could be programmed.
Buscando la Fuente







A First Taste - print on canvas, 10x8
Un Primer Gusto











 Bodegón con Ciruelas y Chocolate







Estaba Tan Involucrado







La Cervecería







In the exploration of unknown frontiers, you never know what surprises will come up next. With persistent curiosity and careful thinking, clearly defined facts emerge from the chaos of multiple variables and experimental uncertainty.
El Vallista







AUTOENSAMBLAR





La naturaleza tiende a construir sistemas dinámicos ensamblando micro en macro y macro en supermacro. El autoensamblaje es un proceso natural omnipresente a escala molecular (cristales, virus, citoesqueletos) y escala macroscópica (conejitos de polvo, dunas de arena, estrellas).









El Camino Que Sabe 







Noche Silenciosa







Árbol de Autoensamblaje











Reordenamientos







Experiments conducted within a fluid medium with very tiny molecules present a unique impasse when the experiment relies upon those molecules coming into contact with each other – such as when multiple molecules bind together to form a larger functioning unit. The pieces are so tiny, and the drop of fluid so large that the molecules are unlikely to find each other, unless they can be designed to be attracted to each other.
Affinidad







Enjambre y Forma







formas de ser









Autodidacta







Bodegón Flotante







Luz Interior







When we're comfortable within a setting, particularly a natural one, our energies and attention may readily merge with the flow of energy, of events, and the order of things all around us, leading to great ideas and insights. Those with access to resources, liesure, and perhaps connections are best positioned to act on these energies and events.
Avanzando







REINOS OCULTOS









Thrill seekers love to probe the unknown. For some, it’s the fresh powder on the slope of an uncharted mountain. For others, it’s the unexpected terrain of a new scientific field. For a few, it’s both.
Andando Más Allá







Bodegón con Actinolit







Cielo Y Tierra







SERIE DE CIENCIAS ANN ERPINO Y ERIK WINFREE – DIAPOSITIVAS





  • Rain of Abstractions
  • DNA is highly ordered to avoid random tangling between DNA molecules. DNA is highly condensed to allow long linear DNA molecules to reside in a very tiny space, the nucleus.
    Kelp Forest
  • When we're comfortable within a setting, particularly a natural one, our energies and attention may readily merge with the flow of energy, of events, and the order of things all around us, leading to great ideas and insights. Those with access to resources, liesure, and perhaps connections are best positioned to act on these energies and events.
    Forging Ahead
  • People have long used biological materials -- skin, hair, bone, wood -- as the building material for crafting technological marvels -- leather boots, wool sweaters, ivory knives, sail boats. Today we're able to use biological polymers such as DNA, RNA, and protein to craft marvels at the molecular scale as well.
    Vase Makers
  • The nematode Caenorhabditis Elegans is mathematically unique in that wild-type individuals contain exactly 959 cells. The position of each cell is also precisely determined. C. Elegans is transparent, so cell function and lineage are easy to track.
    959
  • When informational molecules such as DNA, RNA, and proteins fold from a floppy linear chain into a concrete shape, such as an enzyme or other nanomachine, the process is directed by subsequences along the chain that search for matching subsequences elsewhere in the chain, and then bind and lock up to stabilize the fold.
    Molecular Introspection
  • We can't know how life started on Earth or how it starts elsewhere, but exploring how simple chemicals assemble, react, and evolve in the laboratory gives scientists an enriched and more grounded imagination for what the first organisms may have been like — and has already led to interesting biotechnologies.
    Andy Ellington
  • The Sierpinski gasket is a mathematical fractal constructed by repeatedly cutting the middle out of each triangle. Or, more akin to crystal growth, it may be generated by starting with a layer of 0′s with a single 1, then building new layers by placing a 0 above and between each pair of identical bits, while placing a 1 above and between each pair of differing bits.
    Wings
  • Exposure at a young age to the joy of discovery can cause serious imprinting and make a life-long impression upon one’s curiosity factor.
    A First Taste
  • At the human scale, a flat surface is a simple thing. But closer in, its incredible complexity becomes apparent. Molecular engineering can control some of that complexity, using self-assembly to coat the surface and place complex molecules in specific locations.
    Molecular Fields Forever
  • The principle of least action states that, of all possible paths a particle, such as a photon, could take, it will take the one with minimal integrated energy. Analogous optimization principles are used in software that finds the best route from place A to place B, finds the best price for a concert ticket, or finds the most likely interpretation of data.
    Distilled Convergence
  • Objects exchange molecules upon contact. Residue left by each can start a new growth pattern, such as crystallization, on its new host.
    Dragonflies
  • For everything that you see, there's more that you don't see.
    See Saw
  • Machines can learn, at least a little. With scientific advances they will continue to become smarter, and eventually may discover and perceive the world in their own way.
    Adventures In Mechanical Thinking
  • Biochemical experiments often require tiny volumes of liquid - microliters, or less…a fraction of a raindrop.
    Droplet
  • Control theory studies how feedback loops between sensors and actuators can be used to make robust responsive systems, from a car’s cruise control to robots in a factory, or biochemical circuits within a cell.
    Recurrence
  • Throughout evolutionary history an astounding variety of life forms have been chanced upon, most of which would look alien and bizarre to us now. During the Cambrian era over 500 million years ago, many animals with very strange body plans and weird appendages (as strange and weird as ours might seem to them) evolved. Each of the life kingdoms that we know today -- the protists (single-celled eukaryotes), monera (prokaryotes), archaea, fungi, plants, and animals -- began with a unique distant ancestor.
    Let’s Do This
  • Quantum Bridges
  • Advanced medical therapies involve molecular robots programmed to 'crawl' around the outside of targeted cells (such as cancer cells) after recognizing diagnostic cell-surface markers that identify them as malign. As the molecule interacts with the cell membrane it effectively cuts it open, destroying the cell.
    Process of Elimination
  • Some scientists believe that free-range, pre-life organic molecules spontaneously joined together to make the first organisms. Joining and scission can be seen in the laboratory when scientists create self-assembling nanotubes known as `living polymers.'
    Joining/Scission
  • In an emulsion, water droplets become surrounded and separated by oil. Each water droplet can be filled with a different set of (perhaps random) molecules, whose behaviors can then be observed. Scientists can use these droplets to run millions of tiny experiments in parallel.
    Zoo of Pearls
  • Vestiges and fundamental qualities of our earliest ancestors remain encoded within us today. Whether plant or animal, fungus or virus, each living thing culminates froma very long chain, bringing information from primordial times.
    Inner Scaffolding
  • Chemical processes can create patterns similar to the spots on leopards, the patchwork on giraffes, the stripes on zebras. More complex patterns could be created if chemistry could be programmed.
    Seeking the Source
  • In a short story by Stanislaw Lem, Mymosh accidentally came into being when a jettisoned object from a passing spaceship rattled a post-nuclear garbage dump, causing various objects to tumble, collide, and attach, forming a thinking being.
    Mymosh the Self Begotten
  • Computer chip technology is basically artificial geology. Lithography, the technique used to carve wires and transistors into a silicon chip, can build many layers of structures on a slab of silicon, but to truly master the art of turning inanimate rock into a thinking machine requires understanding the nature of the material. It will tell you what it can do; listen to the silicon.
    Rock Whisperer
  • Molecules, molecular systems, and materials can be simulated and designed on computers, allowing visionary scientists to imagine and create environments from atoms on up.
    What Dreams Are Made Of
  • DNA microarray chips allow doctors and scientists to read the internal workings of a cell. A single chip can have hundreds of thousands of pixels, each of which can detect the presence of RNA for a specific gene, or a certain genetic mutation. This information can lead to novel discoveries and insightful diagnoses.
    Data Dancer
  • Life may have arisen from naturally occuring mineral crystals that replicated by spontaneous mineralogical processes, eventually providing the framework for, and stimulating the production of organic molecules which form the basis for modern organisms. (Also see ‘Terrestrial Matrix’)
    The Loss of Entropy
  • Each of 100 trillion cells in your body has its own DNA, its own molecular factory for building proteins, and its own biochemical circuitry for making decisions. Though self-contained, these cells depend upon each other, and function together as a unified whole. Some species, such as slime molds, live as independent single-celled organisms in their early life, then unify with other slime mold cells into a multicellular organism for the latter part of their life. Roboticists may one day develop small robots that can similarly assemble themselves into a larger, unified meta-robot.
    Come Together
  • Interstellar travel could conceivably be managed by self-assembling spaceships, which would land on a convenient planet or meteor, assemble new parts from available raw materials, make repairs, and be on their way again.
    500 Year Plan
  • A.G. Cairns Smith hypothesizes that clay crystals begat life. The crystalline latticework, as it grew and broke apart, provided scaffolding for new crystal growths. As these crystals incorporated more organic molecules into their structure, with reproductive advantage, the organic molecules eventually became sophisticated enough to co-opt their host’s matrix and float away, perhaps on the next tide, as autonomous life. (Also see ‘The Loss of Entropy’)
    Terrestrial Matrix
  • Behind a seemingly impenetrable barrier is often a calm place of quiet sustenance; getting there may be easier, if more circuitous, than one thinks.
    Rock Nest
  • A microfluidic chip is a network of tubes, valves, reaction chambers and sensors packed into a small device capable of making sophisticated medical diagnoses.
    Digital Healer
  • Those who have an instinct for assessing and doing what needs to be done, and for taking care of others' needs, lift the spirits and improve the lives of those around them.
    Floating Still Life
  • Self-healing objects are capable of repairing damage to their structure. They range from simple (e.g. water) to complex (e.g. a salamander’s tail). In molecular biology, self-repairing fragments are good candidates for mutation, and therefore evolution. The process of mathematical discovery may itself be self-healing, as it balances the confusion caused by real-world paradoxes.
    A Rip In The Fabric
  • Nature builds powerful computers, your brain being a prime example. Molecular self-assembly allows scientists to create electrical circuits by growing them.
    Forest of Wires
  • To power nanomachines, a molecular fuel must store energy in a stable form - stable until it's released.
    Heat Capacity
  • Distributed molecular robots are herds of simple machines communicating with each other to accomplish collective tasks. Like ants, these robots can attach to each other to form chains or walk on top of one another to create collective superstructures.
    Migratory Procession
  • In the brain, visual scenes are broken down into elementary pieces - edges, colors, corners, motion - from which more complex perceptions are derived - textures, shapes, actions - and eventually the important features of the scene are recognized. As with dreaming, a deeper look into the visual cortex reveals an even finer disintegration of each piece of a scene, pixelated and then reconstructed inside an observer’s head.
    Fragmented Vision
  • Nanotubes and Buckyballs (named after Buckminster Fuller) are atomic-scale, chicken-wire-like mesh cages, whose remarkable properties allow intriguing fundamental science and new technological applications. Found in the soot of burnt carbonaceous material they, like diamond, coal, and graphite, are formed by natural processes.
    The Miracle of Soot
  • Intuition becomes stronger with use and nurture, and has a powerful way of breaking through the conventions and constrictions imposed by traditional approaches.
    Inner Light
  • With the right insight and careful touch, DNA can Be programmed to assemble itself into incredibly complex nanoscale objects called 'DNA origami'.
    The Weaver
  • Ever since Pythagorus and likely before, mathematicians have seen the world as being composed of numbers, which has led to great insights.
    Portrait of Peter Gacs
  • When listening to music, neurons in your ears encode the sounds into a sequence of electrical signals, called spike trains, that record the rhythm, tones, and texture of what you’re hearing. The spike trains are sent to your cortex, where the sounds are perceived, enjoyed, and interpreted.
    Neurotango
  • At the core of each being is a self-contained informational unit awash in currents and forces, processing, deciphering, responding to its environment. Sentient immersion is more critical to wildlife than to industrialized beings.
    Nerve Creature
  • The technological shift in electronics from analog to digital was paralleled by a paradigm shift in mathematics, with discrete and combinatorial maths replacing traditional continuous analytical maths. Continuous objects are now converted to discrete representations for processing on digital computers.
    Discretization
  • Intermingling matter on all levels, from neutrinos to the cosmos, necessarily exists in a container. The nestling importance of 'empty' space is often overlooked simply because it 'isn't there.'
    Intermingling
  • In science, you can seldom directly see what you’re studying. Experimental results are colored by how a question is posed and what experimental apparatus is used. This issue is particularly prominent in quantum physics.
    Maple Leaf
  • How, and whether, one perceives the unseen energetic worlds around and through us is a matter of ability and choice. To perceive, and perhaps channel vibrational inputs gives practitioners special access to wondrous and fascinating worlds.
    Entangled Realms
  • Groups of cells (particularly in the nervous system) and groups of organisms, such as a flock of birds, a school of fish, or a colony of ants or fireflies, can work together in concerted, synchronized patterns, as if following signals perceived only by their group. Scientists may learn to observe and detect these signals.
    Synchronization
  • It’s hard to catch a molecule; they’re too fast and too small. So scientists get others to catch them by making molecules to catch molecules. Then they can be studied and programmed.
    Captured
  • Interdisciplinary science requires an ability to synthesize many strands of knowledge, to bind them together and test their strength, then extract pertinent information.
    Rainbow Fiber
  • It’s a simple matter to tie a complex knot, or set a combination or code. It’s much harder to untie the knot or crack the code.
    Undecipherable
  • In the exploration of unknown frontiers, you never know what surprises will come up next. With persistent curiosity and careful thinking, clearly defined facts emerge from the chaos of multiple variables and experimental uncertainty.
    The Hurdler
  • Mathematical abstractions never look like the real thing, but they are often as powerful, and are frequently more conceptually illuminating, in an abstract way.
    Almost Real
  • Mathematics studies perfect objects - the Platonic ideal - but often the proofs can be messy and confusing.
    Shadow of Perfection
  • With determination, and great patience, the seeker is often rewarded with the discovery of unique and surpassing results.
    Hatchling
  • Communication comes in a variety of forms. Some signs and signals, such as laughter, or a wave, or a sigh, are readily understood by just about anyone, and even by some animals. Others are esoteric, perhaps only understood by one or a few.
    Notes to Self
  • The elegance of simplicity is a coveted end in scientific communities across time, place, and field of research. "What can be done with less is done in vain with more." Willem of Occam
    Grun
  • When a new lab gets started, it’s important to keep it fueled with enthusiasm, energy, and especially midnight snacks.
     Still Life with Plums and Chocolate
  • Scientists and artists become absorbed in their work, forgetting to eat, or losing track of time, place and (when it’s really good) even self.
    I Was So Involved
  • Scientific investigation is never complete. From the vantage point of new experience and knowledge come new directions of pursuit.
    If You Dare
  • Entire organisms - be they trees, whales, frogs, or humans - develop from a single cell. When cells divide, each half innately ‘knows’ which part of the organism it should become next.
    City of Life
  • Many great and inspired ideas have occurred to thinkers while completely disconnected from their mental task. A long sought-after idea or solution may spontaneously surface during a moment of relaxation and distraction, an “Aha!” moment.
    The Brewery
  • When light bombards a molecule, a photon may be absorbed, in which case the extra energy causes the molecule's bonds to vibrate more vigorously. Some of that extra vibrational energy dissipates into the molecule's surroundings as heat. If the energy is not completely dissipated, the vibrations may align to create and emit a new photon with lower energy and a (usually) longer wavelength; that is, they fluoresce.
    Fluorescence
  • Organisms and their parts somehow 'know' when to stop growing. As computers count in an algorithmic, logarithmic or binary way, so does biology 'count' in its own biochemical way.
    Core Concepts
  • Self-assembly is a process that spontaneously creates order. At the molecular scale, self-assembling components don't ‘know’ where to go - but they get there. Particles combine and settle in so many ways, randomly fitting together, that eventually, bit by bit, they become complex and can build even further.
    Rearrangements
  • In our multifaceted lives, those things which anchor us to the earth, which ground us and provide a base, can allow our subtle minds to roam, to dream, and to visit faraway realms in our thoughts. Here thoughts and sensations travel faster than light.
    Sky and Earth
  • In art and science, achieving a given outcome is one small part of a long process. Desired outcomes are there to be realized, and with discipline and perseverance, they'll eventually be attained.
    The Force of Impossibility
  • The naturalist feels an affinity to the myriad products of nature in all their peculiarity and beauty. Each of us being unique, we're attracted to, or intrigued by a different set of textures, processes, functions, values, and colors of things. These things and combinations affect us in silent and invisible ways, shared across humanity.
    Still Life with Actinolite
  • Eventually, one must leave the safety of home and set out to make their way in the world, where one's eyes are opened by possibilities and dangers, by the edifices left behind by their predecessors, and by the wonders of life’s machinery.
    Butterfly’s Path
  • The retina is a complex network of neural cells that detect light and immediately begin signal processing to reduce noise, increase sensitivity, and identify regions of contrast and motion. While the insect eye consists of a regular hexagonal grid of nearly identical cells, each with its own lens and neurons, a mammal’s eye has a single lens and many somewhat irregularly spaced photoreceptor neurons.
    Sight
  • Material forms require an array of forces, weights, densities, and other qualities - qualities which are inherent to the object as a whole, and a similar array of forces, weights, and densities within each particle that comprises it.
    Physics In-Formation
  • If you draw a random squiggly line on paper and, at the intersections clarify which part goes over and which goes under, there is, imaginably, a surface contained within your squiggle. A thin wire bent into a twisted but closed curve and dipped into soapy water reveals such a surface.
    Seifert’s World
  • Self-assembly is a ubiquitous process at the molecular scale (crystals, viruses, cytoskeletons) and macroscopic scale (dust bunnies, sand dunes, stars). Tree forms are also ubiquitous in nature and culture, and are self-organizing at many scales (rivers,carbohydrates, traffic patterns). These universal forms can be seen seemingly everywhere.
    Self Assembling Tree
  • Preparing a sample for atomic force microscopy, complex self-assembled molecules settle onto a mica surface, where they will soon be imaged. (Also see “Wings.”)
    Silent Night
  • Some structures are made from strings and struts, (like a suspension bridge, or the bones and tendons of living creatures) where every strut is separate, and every cable is pulled taut in such a manner that the structure doesn’t collapse. The tensional integrity of an object or system derived from the balance of tension members, as opposed to compression struts, is its tensegrity, aka: floating cohesion.
    Tensegrity
  • Occasionally someone’s life story may seem scripted or contrived to the point of being impossible - a series of extraordinary events, coincidences, great hardships and crucial choices leading to that person’s unique work and expertise, as if by recipe.
    Against All Odds
  • An individual is a self-organized collection of smaller individuals. There are often two parts: global interactions of roving elements (such as bees or blood cells) and local arrays of geometrically arranged elements (such as nests or brain cells).
    Swarm and Form
  • Often the best scientific result is the simplest. A solution or discovery may, with hindsight, be so uncomplicated and obvious that it's surprising, or elegant. Yet to approach that simple truth may have required sophisticated instruments and complex methods to explore thousands of possibilities.
    A Prepared Mind
  • All material objects are made of just one thing: atoms. If you could separate the atoms in one object, and put them back together again with extreme precision, you could make another object.
    Treasure Chest
  • Molecular engineers can design and synthesize complex polymers that grow in almost lifelike ways. Like a spider, an engineered molecule can trigger insertion of polymer subunits behind it, thus effectively "excreting" a thread to which it remains attached. As engineering frontiers expand, even more lifelike behaviors will be attainable.
    Hanging Gardens
  • Synthetic biology is the engineering and construction of molecular devices that work inside cells. The construction materials are restriction enzymes to cut DNA, polymerases to copy DNA and RNA, ribosomes to translate RNA into protein, and myriad chemical tricks for finishing touches.
    Tinker’s Molecular Workshop
  • Consonance and Dissonance
  • Experiments conducted within a fluid medium with very tiny molecules present a unique impasse when the experiment relies upon those molecules coming into contact with each other – such as to bind together to form a larger functioning unit. The pieces are so tiny, and the drop of fluid so large that the molecules are unlikey to find each other, unless designed to attract each other.
    Affinity
  • Some of the most precious things in science - and in life – are the ability to learn for yourself, to tap into your own unique perspective and interests, and to do it with a sense of adventure.
    Autodidact
  • A cell’s cytoskeleton consists of a network of molecular-scale "I beams" that hold the cell in its shape. Some engineered cells can crawl by growing their cytoskeleton on one side while dissolving it on the other side.
    Cytoskeletal Motor
  • Crystals can grow in surprisingly complex ways. Synthetic bismuth crystals grow as square-angled spiral staircases. With the ability to design macromolecules, it’s now possible to create crystals with a programmed growth path, and which can “intelligently” respond to obstacles it encounters.
    The Path That Knows
  • Computer programmers can be quite imaginative. The term “bug” itself is a fanciful metaphor. Some programmers have bugs in their programs; others have cuttlefish.
    Cephalopond
  • Thrill seekers love to probe the unknown. For some, it’s the fresh powder on the slope of an uncharted mountain. For others, it’s the unexpected terrain of a new scientific field. For a few, it’s both.
    Going Beyond
  • As intelligent beings who learn from their environment, we contain within ourselves mirrors of the world, and even mirrors of ourselves. One remarkable example is that if you look at the brain’s sensory and motor cortex and ask what part of the body it pertains to, you get a (distorted) map of the body.
    Homunculus
  • Your brain hasn't always known that your arm is your arm. It may have learned it the same way that someone with a prosthetic limb learns to experience the artificial limb as part of their own body. Extensive tool-use (imagine a racquetball racket, violin, or even a mechanized prosthetic) can also lead to the sense of the tool or machine being a part of your body.
    Inside Outside
  • Chemical processes can create patterns similar to the spots on leopards, the patchwork on giraffes, the stripes on zebras. More complex patterns could be created if chemistry could be programmed.
    Reaction Diffusion
  • In programming, instantiation is the creation of a real instance of an abstraction or template such as a class of objects or a computer process. In mathematics, objects (such as sets or functions) can be defined that are impossible to compute. Yet these impossible objects can provide insight that clarifies possibilities.
    Instantiation
  • Waterfall
  • Theta Bay